The work reports the development of titanium-organic nanostructure synthesis on a nano-titanium surface. The conditions for reproducible manufacturing of the brush-type titaniumorganic nanostructures with calcium-phosphate inclusions via ML-ALD technique are studied. The technique for composite coating synthesis of titanium-organic brush-type nanostructures on nano-titanium surface with calcium-phosphate structures inclusions acting as osseointegration promoters is developed. The adhesion properties of composite nanocoating to osteoblasts MC3T3-E1 cell line were evaluated. The developed composite coating can be a promising material for implants with accelerated osseointegration. |
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